An Expanding Chemogenomic Toolbox Gives Kinome Research a Welcome and Much Needed Boost
The human kinome includes 500+ druggable targets, with 35+ small molecule kinase inhibitors approved by the FDA since 2000. Remarkable. Despite the... Read More
Chemical Probes Portal – Know Your Selectivity!
The Chemical Probes Portal is a new online resource for anyone using tool compounds in their research. We can learn a lot... Read More
The Key to Designing a Kinase Screening Project
The key to designing any scientific study is to carefully define the question you are asking – and designing a kinase inhibitor... Read More
3 Key Trends in Drug Discovery Outsourcing for 2016
In 2011 the pharmaceutical industry was presented with a major challenge. The peak of the patent cliff was approaching with over $30... Read More
Kinome-wide Profiling of Existing Chemical Assets: A Powerful Strategy to Jump-start New Drug Discovery Programs
Kinase inhibitors are among the fastest growing classes of FDA-approved drugs, and it has been satisfying to see that three have now... Read More