Slideshow

Glucagon-like peptides, GLP-1 & GLP-2, are well-researched, metabolically significant peptide hormones secreted from the L-cells of the small intestine in response to... Read More

Q: WHAT IS THE IMPORTANCE OF GPCRs IN DRUG DISCOVERY AND DEVELOPMENT? A: GPCRs have long been regarded as a low-hanging fruit... Read More

Drugs interact with living physiology; an in vitro assay of drug activity can be considered a snapshot of the full movie seen... Read More

Cytokines and their receptors have emerged as major drug targets for inflammatory and autoimmune diseases, allergies, and, more recently, in cancer immunotherapies... Read More

Application of GPCR Pharmacotrafficking & Cell-Based Assays Orphan G Protein-Coupled Receptors (oGPCRs) comprise one-third of the druggable GPCR space1. Despite their pharmacotherapeutic... Read More

Importance in Drug Discovery & Development for Quality Testing Programs Cell-based assays have emerged as crucial tools for basic and applied research.... Read More

Cellular membrane proteins play important functions in many biological processes. Understanding their roles often requires that these proteins be isolated from their... Read More

Information on compound-target engagement obtained from traditional in vitro binding assays differs greatly from that in a physiologically relevant model (in vivo).... Read More

Whether you’re looking to screen a library of drug candidates for binding to a particular target protein, checking drug cell membrane penetration,... Read More